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Of course, Portugal is the favorite in this match even without Ronaldo. The only question is whether Luxembourg will be able to score a goal?
I agree that is the question because the odd of Portugal of less than 1.10 says that this game should have quite some goals and prediction pages for football betting are all pointing to at least Over 3.5 goals as the main bet with near 1.80 odd for such game.I think we will see goals but most likely it will be very difficult for Luxembourg to score a goal to Portugal in Portugal home when we know that their goal difference is 15:0 meaning they have not conceded a single goal yet and surely Luxembourg is not the team to do it,to score their first goal against them if they play seriously,they are already qualified though and they may not give a damn about this game and they can concede quite some goals.
Luxemburg have surprised most people with their latest performance,since nobody expected them to display such brilliant performance in their matches. Ronaldo playing or not playing wouldn't change anything in this match since Portugal have qualified already.