BTC-e and Cryptsy are the ones I use primarily, but if I'm dumping coins that aren't on those sites, I have to go where they're traded. Cryptsy has a massive amount of coins to trade with and is the most practical, but sometimes having BTC-e's lower Bitcoin value or the like is favorable. BTC-e and BitFinex are actually lower than most trading sites because of the fact that they
offer their traders leverage. This makes it so that someone with a leverage of x2 can trade with $200 instead of $100. While this sounds like a good deal, if you loose the $200, you have to pay back the $100 leverage. That makes for the value to be usually lower than other sites.
I hate Cryptsy for many reasons, one of them is that they allways seam to pump value to useless coins and then dump afterwards.
Over and over again, it alse happens that certain sh*tcoin that i have is getting pumped, and when i transfer it there, it doesnt get credited until the dump is over, even tho it has more than enough confirmations.
Responses from support are allways useless, they resolve issues, but only after loss is certain.
On the other hand, btc-e has shown me nothing but good experience, im only sad they removed skrill (ex moneybookers) withdraw
It was so handy..