It will really be bad for the image of Casimero if he gets knockout by Naoya Inoue. However, we have seen great fighters losing to Inoue so at least Casimero gets his chance against Inoue (if ever they will fight).
Yes, I would also like to see Inoue at least stay in this division for good and fight not just Casimero but other contenders as well like Luis Nery so that it can really cemented his legacy at 122 lbs before moving to another weight class that he wants to conquer.
This situation could imply one thing: Casimero's journey might face obstacles. His popularity largely stems from his winning streak, and there's ongoing anticipation that he'll eventually face Inoue. While the majority believes Casimero would lose, it's worth noting that Casimero has been unpredictable in the past and has triumphed as an underdog. So, it wouldn't be surprising if he managed to defeat Inoue, who is expected to be the heavy favorite.
Have you noticed that the names Casimero and Inoue are still frequently discussed? It appears they are considered among the best fighters in their division.