I think his career is totally over now since we can't see a furious Donaire as same as before. Age is showing up and that's the reason why he keep losing to much younger opponents.
I hope his wife will tell him that, he is listening to his wife and also a fighter herself for a boxer the last to give up is the mind and the heart, on this match his speed and power are not there anymore I hope he and his family will see this fight and decide to give up, we all want Donaire to have a graceful exit but two successive losses where he is badly beaten is not a motivation to continue, he is multiple champions, it has been a great journey after he won the title against Vic Darchinyan with a one-punch, fifth-round knockout (KO), the best time is now we don't want him to get badly injured in his next fight.
For sure her wife tell him to consider retirement but I guess Nonito is the one arranging a fight for his self then just tell it to her wife that he like to fight for some particular fighter. Its his passion so I guess her wife just supporting Donaire this is the reason why he still on the canvass fighting.
But as of the moment he got 2nd straight losses so I guess this is enough. Nonito need to retire before his career and health will be ruined since he can continue his passion by teaching new generation of Filipino fighters which have potential to became a world champions in future.