I think alternating your bets will give you more loss than staying at Hi or Lo to some point?
There is no difference. Any bet is independent and it does not depend on the previous one.
For example when you play with 2x miluiplier, your chance of winning is 47.5%. It doesn't matter you bet on HI or LO.
You are right. Every week there are at least 200 million tickets. If you have 40,000 tickets, your chance would be (40,000/200,000,000)*10=0.002=0.2%
It's a small chance and the probability of winning a prize every 3-5 rounds is really low.
What is this calculations? I do not quite understand it, dont you think that (40,000/200,000,000)*100%=0.02% chance? Is this not hownthe calculations should be? Correct me if I am wrong. I am just bad at this calculations but like I said before I do try using 100,000 tickets on each weeks but of course does not hit this yet. May be I should try to try more? From what he said before that it will work after 3-5 games, am I close to be the winner soon?
That's because there are 10 winners every week. I multiplied that by 10.
With 100,000 tickets your chance is 0.5%.
Note that I assumed that there are 200 million tickets. It can be different.
Be careful not to create a expectation with people that they would have a better chance of winning, if they have 500+ tickets, because the odds are still very much against them with that amount of tickets. 
