Losing mane and neuer would be a very big disadvantage for Bayern but the club has prepared some potential players that can replace mane's position. The match will come in February and there are still lots of time remaining before the match will begin next year. We have not yet even entered the last week of this month.
The match between PSG and Bayern Munich would have been more competitive if Mane and Neuer is going to be available no doubt but there is a need to be worried because even though Bayern Munich gets a replacement for Mane and Neuer they will need time to adapt to the playing pattern of Bayern and that would be a problem to Bayern Munich who will not have all the time before the match in February, Bayern Munich players may also use the players in the team to play the game but it will be a big risk for them because playing against a team with players like Messi, Mbappe which are injury free for now needs good players to stand against them and Neuer's position as the goalkeeper is also going to affect the Bayern team.