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I think La Liga will survive. It will for sure take a hit but we've all seen the GOATs come and go. Becham left United and the club didn't fade. Ronaldinho left Barca, and Luis Figo (although haha we all know where to) and Ronaldo (original) left Real but nothing faded.
New stars and new heroes will fill the void.
El Clasico is something else though and yes, maybe that will need new heroes and villains.