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Earth not being an isolated system doesn't have anything to do with complex life in the presence of cause and effect. Why not? Because we see devolution all over the place. But we don't see anything evolving except where we have changed the meaning of "evolution" to simply mean "change." Cause and effect produces change.
Complex from simple, if it happens, is induced to happen by cause and effect. This means that something way more complex caused the simple to complex to happen.
Entropy is proof of a beginning. If it were not as widespread, or if we could ascertain that it didn't work for everything, then it might not be.
Now we are getting somewhere. Something causes mutations, morphological changes. You got it right.
Did you know that the rate of gene mutation goes through the roof in space? Astronaut's gene mutations increase in space, and 'come' back down when they return to Earth.
Environment causes things to happen.
The same way, something caused the Big Bang to happen. I bet you in 100 years we'll know what it was. And I bet you we'll have bunch of other unknowns that we'll be looking to find answers to.
Imagine if you lived 600 years ago, your 'proof' of God would be diametrically different.
It is very tempting to say that something powerful and unknown is responsible for all the universe(s). Right now, we have the Dark Energy and Matter that we do not understand. Are you going to call it 'God'?