I think we fail to acknowledge one glaring fact of players' willingness or non willingness to support the new manager/coach.
This should be a concern for Amorim, because it is until the coach has warmed up to the players currently in the squad and have bonded with them that he can do and know which players needs to be sold or transferred for free.
The goal will remain same for him and that's to bring Manchester United to the top of the table and make them qualify seasonally for the champions League which is the hottest cake for professional footballers.
This is going to be the biggest task Amorim will face and it could make or break the entire season as well. If players are happy with him, then they are going to do fine, back in the day when Mourinho was here and Bruno was a star, they had this Portuguese team, a few players there, and now they are mostly Dutch and the Dutch dude left. So, if those player are mad that Amorim took their coaches position, they will be pretty upset and not play well and not get along with the coach as well.
So, we are going to see a bit back to Portugal from them probably, they are going to wait until summer for that though, maybe one or two small transfers during January but that's it. They need to figure out players that will play well for Amorim and listen to him and care about him. Doesn't matter where that player is from, if a Dutch one does that then that's fine too but they have to care about what he says at all times.
This is a big risk they are taking right now, and I have no idea how this will end up. It could be a great deal and they could start winning plenty of games, or it could be a very bad decision and they could end up with a bunch of terrible results again which will not be ok at all.