Almost every single gambler will have remorse if they have lost everything to gambling, you don't realize that you are losing everything until at the end, you see that a very small amount is remaining from your game account and then you start thinking that you should gamble this as well only with the hope that maybe you manage to win something big from it, and when that doesn't happen, that is where it starts.
You might not feel remorse if you were gambling with a limited budget that you had set only for gambling, in such a case, you won't feel that bad because you already have made up your mind that you might win but you may lose as well.
Just once, I had it so terribly because it was the first ever money I earned and then I lost it on gambling and I swore off gambling for a long time after that, didn't gamble for god knows how long. When I came back, I had that in mind and I knew that gambling is a net loss and there is no winning here.
Doesn't mean that every single time you gamble you will end up with a loss, I had those crazy 100x or more returns as well, definitely was a fun feeling when I won that but even then I knew that I will not be earning anything from it and the long run I will lose at least that much as long as I kept on trying. This is why I ended up limiting my budget very well and I do not end up gambling excess amount, no need to risk anything for something I know I am going to lose.
That's definitely a good decision to have a limited budget for gambling and not spend everything that you earn or have on gambling only with the hope that you might win more than what you have as we all know the house always wins in the long run, so whatever you make in gambling will eventually be lost if you don't know when to stop, and even if you stop at that moment when you've won something, you will still gamble it back later if you don't limit your gambling budget.
I don't think that there will be even a single gambler out there who doesn't feel remorse for losing something big or very important ever in their lives in gambling, it happens to everyone but some will learn from it and others will still continue gambling.